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Updated: Dec 21, 2025

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Management of acute kidney injury in COVID-19
Mohamed Hassanein1, George Thomas1, Jonathan Taliercio1
1Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic.
Abstract:
Acute kidney injury has been reported in as many as 29% of COVID-19 patients. Reported risk factors include elevated baseline serum creatinine, elevated blood urea nitrogen, acute kidney injury, proteinuria, and hematuria. Suspected causes include sepsis and acute tubular necrosis resulting from renal hypoperfusion, cytokine release syndrome, direct viral invasion, renal medullary hypoxia secondary to alveolar damage, rhabdomyolysis, and cardiorenal syndrome due to viral myocarditis.
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