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In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess...
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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Related Experiment Video

Updated: Dec 21, 2025

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Cognitive Function in Liver Transplantation.

Somaya A M Albhaisi1, Jasmohan S Bajaj2

  • 11Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA 23298-0341 USA.

Current Transplantation Reports
|May 22, 2020
PubMed
Summary

Liver transplantation (LT) can lead to neurological complications in up to 30% of patients. This review explores neurocognitive changes post-LT and offers recommendations for patients, caregivers, and physicians.

Keywords:
Brain functionCirrhosisCognitionCognitive reserveTransplant

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Area of Science:

  • Neurology
  • Hepatology
  • Transplantation Medicine

Background:

  • Liver transplantation (LT) is a curative treatment for end-stage liver disease.
  • Neurological sequelae and quality of life after LT are significant concerns.
  • Understanding post-transplant neurological changes is crucial for patient management.

Purpose of the Study:

  • To review neurocognitive changes following liver transplantation.
  • To identify factors contributing to neurological complications post-LT.
  • To provide recommendations for patients, caregivers, and physicians.

Main Methods:

  • Literature review of studies on neurological complications after liver transplantation.
  • Analysis of incidence and types of neurological symptoms observed post-LT.
  • Discussion of potential underlying mechanisms for neurological sequelae.

Main Results:

  • Liver transplant recipients have a higher incidence (up to 30%) of neurological complications compared to other solid organ recipients.
  • New-onset neurological symptoms can occur even without prior hepatic encephalopathy (HE).
  • Various factors may directly impact cognitive function post-LT.

Conclusions:

  • Postoperative neurological symptoms may stem from HE sequelae, cirrhosis-related cognitive impairment, or undiagnosed neurodegenerative disorders.
  • Further research is needed to elucidate the precise mechanisms.
  • Recommendations are provided to optimize care for LT patients experiencing neurological changes.