[Preclinical management of cardiac arrest-extracorporeal cardiopulmonary resuscitation]
Related Experiment Video
Updated: Dec 21, 2025

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
Published on: May 26, 2023
C Lotz1, R M Muellenbach2, P Meybohm3
1Klinik und Poliklinik für Anästhesiologie, Direktor: Univ.-Prof. Dr. P. Meybohm, Universitätsklinikum Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Deutschland. lotz_c@ukw.de.
Background:
The chances of surviving out-of-hospital cardiac arrest (OHCA) are still very low. Despite intensive efforts the outcome has remained relatively poor over many years. In specific situations, new technologies, such as extracorporeal cardiopulmonary resuscitation (eCPR) could significantly improve survival with a good neurological outcome.
Objective:
Does the immediate restoration of circulation and reoxygenation via eCPR influence the survival rate after OHCA? Is eCPR the new link in the chain of survival?
Material And Methods:
Discussion of current study results and guideline recommendations.
Results:
The overall survival rates after OHCA have remained at 10-30% over many years. Despite low case numbers more recent retrospective studies showed that an improved outcome can be achieved with eCPR. In selected patient collectives survival with a favorable neurological outcome is possible in 38% of the cases.
Conclusion:
Survival after cardiac arrest and the subsequent quality of life dependent on many different factors. The time factor, i.e. the avoidance of a no-flow phase and reduction of the low-flow phase is of fundamental importance. The immediate restoration of the circulation and oxygen supply by eCPR can significantly improve survival; however, large randomized, controlled trials are currently not available.
Related Concept Videos
Cardiopulmonary Resuscitation IV: Pharmacological Management
Cardiopulmonary Resuscitation I: Adult
Cardiopulmonary Resuscitation III: AED Use
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Cardiopulmonary Resuscitation II: ACLS Airway Management
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

