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Sedentary behavior and kidney function in adults: a narrative review.
Konstantinos Volaklis1, Temur Mamadjanov2, Christa Meisinger2
1Lehrstuhl für Epidemiologie, LMU München am UNIKA-T, Neusaesser Str. 47, 86156, Augsburg, Germany. k.volaklis@unika-t.de.
Wiener Klinische Wochenschrift
|May 22, 2020
Summary
Sedentary behavior (SB) is linked to impaired kidney function and chronic kidney disease (CKD), especially in older adults. More research is needed to confirm this association and understand the underlying mechanisms.
Area of Science:
- Nephrology
- Public Health
- Epidemiology
Background:
- Chronic kidney disease (CKD) is a growing public health concern, disproportionately affecting the elderly.
- Emerging evidence suggests a link between sedentary behavior (SB) and kidney dysfunction.
Purpose of the Study:
- To systematically review the literature for associations between sedentary behavior and kidney function.
- To evaluate the evidence for SB as a risk factor for chronic kidney disease.
Main Methods:
- A systematic literature search was conducted in Embase and PubMed from January 2000 to December 2018.
- Ten studies (7 cross-sectional, 3 longitudinal) met the inclusion criteria for analysis.
Main Results:
- Sedentary behavior was independently associated with impaired kidney function, including decreased glomerular filtration rate and chronic kidney disease, particularly in cross-sectional studies.
- The evidence from longitudinal studies was inconsistent, highlighting the need for further investigation.
Conclusions:
- Sedentary behavior may be an independent risk factor for reduced kidney function and the development of CKD.
- Further high-quality longitudinal studies are required to establish causality and elucidate the mechanisms linking SB to kidney health.
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