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Related Concept Videos

Acute Pharyngitis01:30

Acute Pharyngitis

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Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
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Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

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Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
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Myocarditis III: Medical Management01:14

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Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
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Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

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Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
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Pericarditis II: Clinical Features and Diagnostic Tests01:19

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Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
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Tonsillitis II: Management01:26

Tonsillitis II: Management

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This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
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Related Experiment Video

Updated: Dec 20, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

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Subacute Thyroiditis After Sars-COV-2 Infection.

Alessandro Brancatella1, Debora Ricci1, Nicola Viola1

  • 1Endocrinology Unit I, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy.

The Journal of Clinical Endocrinology and Metabolism
|May 22, 2020
PubMed
Summary
This summary is machine-generated.

Subacute thyroiditis (SAT) is a thyroid condition often caused by viruses. This case report details the first instance of SAT following a SARS-CoV-2 infection, highlighting a new potential complication of COVID-19.

Keywords:
COVID-19SARS-CoV-2coronavirussubacute thyroiditisthyroidvirus

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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
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Last Updated: Dec 20, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

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Area of Science:

  • Endocrinology
  • Virology
  • Infectious Diseases

Background:

  • Subacute thyroiditis (SAT) is an inflammatory thyroid condition, typically of viral or post-viral origin.
  • The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has led to widespread global health concerns.

Observation:

  • A case of SAT is reported in an 18-year-old woman following a mild SARS-CoV-2 infection.
  • The patient presented with fever, neck pain, and palpitations 15 days post-SARS-CoV-2 diagnosis.

Findings:

  • Physical examination revealed a painful, enlarged thyroid gland with elevated heart rate.
  • Laboratory tests showed hyperthyroidism (high free thyroxine and free triiodothyronine, undetectable thyrotropin), elevated inflammatory markers, and leukocytosis.
  • Neck ultrasound demonstrated bilateral, diffuse hypoechoic thyroid areas, with normal thyroid function and imaging one month prior.

Implications:

  • This report documents the first case of SAT causally linked to SARS-CoV-2 infection.
  • Clinicians should be aware of SAT as a potential, previously unreported, clinical manifestation of COVID-19.
  • Early diagnosis and treatment with corticosteroids led to rapid symptom resolution and normalization of thyroid function.