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In-vitro assessment of lomefloxacin (SC-47111)--a new quinolone derivative

R Finch¹, J Martin, R Pilkington

¹Department of Microbial Diseases, City Hospital, Nottingham, UK.

The Journal of Antimicrobial Chemotherapy

|December 1, 1988

Abstract:

The activity of lomefloxacin (SC-47111) was studied in vitro against 500 clinical isolates. Comparison was made with enoxacin and ciprofloxacin. Lomefloxacin was comparable in activity to enoxacin, but less active than ciprofloxacin. Most Gram-negative bacilli were susceptible, including several multi-resistant strains. Pseudomonas aeruginosa showed variable susceptibility. Streptococci, including Streptococcus pneumoniae, were generally the least susceptible organisms.

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