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Feeding and Swallowing Difficulties in Neonates: Developmental Physiology and Pathophysiology
Sreekanth Viswanathan1, Sudarshan Jadcherla2
1Division of Neonatology, Department of Pediatrics, Nemours Children's Hospital, University of Central Florida College of Medicine, 13535 Nemours Parkway, Orlando, FL 32827, USA.
Insights
Infant feeding milestones depend on gastrointestinal, cardiorespiratory, and central nervous system maturation. Understanding these developmental aspects aids in predicting feeding outcomes and managing difficulties.
Area of Science:
- Pediatric Gastroenterology
- Developmental Physiology
- Neurodevelopmental Pediatrics
Background:
- Infant feeding development is complex, involving the gastrointestinal tract, cardiorespiratory system, and central nervous system.
- Physiologic maturation is key to achieving enteral and oral feeding milestones.
- Feeding difficulties in infants can stem from developmental delays or pathophysiological changes.
Purpose of the Study:
- To review and summarize the developmental aspects of oral feeding and swallowing physiology in infants.
- To provide an overview of the current understanding of pathophysiological changes contributing to infant feeding difficulties.
Main Methods:
- Literature review and synthesis of existing research on infant feeding development.
- Summary of key physiological and neurological factors influencing oral feeding and swallowing.
- Analysis of pathophysiological changes associated with feeding challenges.
Main Results:
- Oral feeding and swallowing development are intrinsically tied to overall infant maturation.
- Cardiorespiratory and central nervous system coordination are critical for successful feeding.
- Understanding developmental trajectories helps in identifying infants at risk for feeding problems.
Conclusions:
- Assessment of infant developmental skills is crucial for guiding feeding management.
- Knowledge of feeding physiology and pathophysiology improves prediction of feeding outcomes.
- Targeted interventions can be developed based on a comprehensive understanding of infant feeding development.
Abstract:
Development of enteral and oral feeding milestones in infants is intricately linked to physiologic maturation of the gastrointestinal tract and its complex interplay with cardiorespiratory and central nervous system control and coordination. Assessment of an infant's developmental skills and maturation can guide us with targeted management approaches and prediction of feeding outcomes. In this article, we review and summarize the developmental aspects of oral feeding and swallowing physiology, and current understanding of the pathophysiological changes associated with feeding difficulties in infants.
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