Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Molecular mechanisms and intervention strategies for age-related macular degeneration.

International journal of ophthalmology·2026

Same author

Objective quality assessment for precision functional MRI data.

Neuron·2026

Same author

Integrating neuroscience across species and scales.

Nature neuroscience·2026

Same author

Herbicide-resistant weeds exploit kinship to reduce allelopathy from crops.

Journal of experimental botany·2026

Same author

MMA++: Effective Multi-Modal Adaptation for Vision-Language Models.

IEEE transactions on pattern analysis and machine intelligence·2026

Same author

Attenuated dynamic impulse control in risky action under the escalating risk and reward in gambling disorder.

Psychological medicine·2026

Same journal

Investigating the Neural Origins of Ear-EEG: A Correlation Study Using Scalp EEG Source Reconstruction.

NeuroImage·2026

Same journal

Hysteresis effects in visual and auditory perception and the comparison of underlying neural mechanisms - an EEG study.

NeuroImage·2026

Same journal

Short-term audio-tactile training affects cortical auditory speech-envelope tracking for incongruent but not congruent stimuli.

NeuroImage·2026

Same journal

Dissociable Neurocognitive Mechanisms of State and Trait Anxiety in Working Memory: Threat-Induced Alterations in Decision Dynamics and Attenuation of Large-Scale Network Reconfiguration.

NeuroImage·2026

Same journal

Neuro-Ocular Amyloid Characterization in Alzheimer's Disease via Cross-Site PET-MRI and Hierarchical Cross-Attention Driven Multimodal Representation Learning.

NeuroImage·2026

Same journal

Whole-brain network dynamics underlying intolerance of uncertainty.

NeuroImage·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Dec 20, 2025

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

Flexible top-down modulation in human ventral temporal cortex.

Ru-Yuan Zhang¹, Kendrick Kay²

¹Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, China; Institute of Psychology and Behavioral Science, Shanghai Jiao Tong University, Shanghai, 200030, China; Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN, 55455, USA.

|May 23, 2020

Summary

This summary is machine-generated.

Attention

Keywords:

Attention Bottom-up processing Fusiform face area Human ventral temporal cortex Top-down processing

More Related Videos

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice

Published on: June 29, 2018

Stimulating the Lip Motor Cortex with Transcranial Magnetic Stimulation

Stimulating the Lip Motor Cortex with Transcranial Magnetic Stimulation

Published on: June 14, 2014

Related Experiment Videos

Last Updated: Dec 20, 2025

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice

Published on: June 29, 2018

Stimulating the Lip Motor Cortex with Transcranial Magnetic Stimulation

Stimulating the Lip Motor Cortex with Transcranial Magnetic Stimulation

Published on: June 14, 2014

Area of Science:

Neuroscience
Cognitive Science
Visual Perception

Background:

Traditional models view attention as a simple scaling or additive effect on neural responses.
This study challenges conventional understanding of top-down attentional modulation.

Purpose of the Study:

To investigate the complex nature of top-down attentional effects in the human brain.
To explore how attention interacts with other cognitive processes during visual perception tasks.

Main Methods:

Functional magnetic resonance imaging (fMRI) was used to analyze brain activity in the ventral temporal cortex (VTC).
Stimulus eccentricity and cognitive task demands were systematically varied.
Data were analyzed from two independent studies with different stimulus manipulations.

Main Results:

Attentional enhancement of neural responses increased as stimuli moved to the visual periphery, where bottom-up responses weakened.
Attentional effects were task-dependent, suggesting influence from other cognitive processes like decision-making.
Observed effects replicated across experiments and generalized to different stimulus properties (contrast, phase coherence).

Conclusions:

Top-down attentional modulation is more complex than previously modeled, involving interactions with other cognitive factors.
A nuanced understanding of perceptual tasks is necessary to accurately characterize top-down neural modulation.
Future research should consider multiple cognitive influences on attention.