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Immune Thrombocytopenia (ITP) in a Pediatric Patient Positive for SARS-CoV-2

Hoi See Tsao1,2,3, Hannah M Chason2, Deirdre M Fearon2,3

  • 1School of Public Health, hoi_see_tsao@brown.edu.

Pediatrics
|May 23, 2020
PubMed

Insights

COVID-19 can present as immune thrombocytopenia (ITP) in children. Testing for SARS-CoV-2 is crucial for pediatric patients with ITP to guide treatment and prevent spread.

Area of Science:

  • Immunology
  • Virology
  • Pediatrics

Background:

  • Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by isolated thrombocytopenia.
  • Viral infections are common triggers for ITP in children, with up to two-thirds having a preceding viral illness.
  • Emerging evidence suggests severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may also trigger ITP.

Purpose of the Study:

  • To report the first documented case of pediatric immune thrombocytopenia secondary to SARS-CoV-2 infection.
  • To highlight the importance of considering SARS-CoV-2 testing in children presenting with ITP.

Main Methods:

  • Case report describing a pediatric patient with ITP.
  • Diagnostic workup included SARS-CoV-2 viral testing.

Main Results:

  • The pediatric patient presented with ITP and subsequently tested positive for SARS-CoV-2.
  • This case confirms ITP as a potential manifestation of COVID-19 in children.

Conclusions:

  • Immune thrombocytopenia should be recognized as a possible presentation of COVID-19 in pediatric patients.
  • SARS-CoV-2 testing is recommended for children with ITP to ensure appropriate isolation and care, mitigating community and healthcare worker transmission.

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