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Updated: Dec 20, 2025

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
Published on: March 8, 2024
A Single Incision Anterior Approach for Transhumeral Amputation Targeted Muscle Reinnervation
Michael C Daly1, Janice J He1, Ryan P Ponton1
1Department of Orthopaedic Surgery, Hand and Upper Extremity Surgery, Massachusetts General Hospital, Boston, Mass.
Abstract:
Targeted muscle reinnervation (TMR) is an evolving technique with promising results for prevention and treatment of neuropathic pain, as well as modulation of control for myoelectric prostheses. The previously described and most commonly used technique for transhumeral TMR combines both an anterior and posterior approach to access the major peripheral nerves of the upper extremity. In this article, we review the literature for transhumeral TMR and describe a more expeditious and efficient anterior-only approach that offers safe access through a single incision.

