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Frontal Trigger Site Deactivation for Migraine Surgical Therapy
Edoardo Raposio1, Francesco Simonacci1
1Plastic Surgery Division, Department of Surgical Sciences and Integrated Diagnostics - DISC, University of Genoa, Genoa, Italy.
Plastic and Reconstructive Surgery. Global Open
|May 23, 2020
Summary
Minimally invasive surgery for frontal migraine offers significant relief. Surgical decompression of cranial nerves effectively treats chronic frontal migraine unresponsive to other therapies.
Area of Science:
- Neurology
- Neurosurgery
Background:
- Migraine is a leading cause of disability, linked to neuronal hyperexcitability and inflammation.
- Compressed peripheral craniofacial nerves are identified as key migraine trigger points.
- Minimally invasive surgical procedures offer a potential treatment for frontal migraine headaches.
Discussion:
- Endoscopic or transpalpebral approaches were used for frontal migraine decompression surgery.
- Supratrochlear and supraorbital nerves were surgically decompressed in 70 patients.
- Frontal migraine was a secondary trigger in 34.2% of patients post-occipital/temporal surgery.
Key Insights:
- 94% of patients with frontal migraine trigger sites reported positive surgical outcomes.
- 32% experienced complete migraine relief, and 62% saw significant improvement.
- The surgical procedure demonstrated a high success rate with no serious complications.
Outlook:
- Surgical decompression of supraorbital and supratrochlear nerves is a viable option.
- Recommended for chronic frontal migraine patients refractory to conventional treatments.
- Further research may explore long-term efficacy and patient selection criteria.

