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Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
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The impact of electroconvulsive therapy on brain grey matter volume: What does it mean?

Harold A Sackeim1

  • 1Departments of Psychiatry and Radiology, College of Physicians and Surgeons, Columbia University, 2124 Moselem Springs Road, Fleetwood, PA, 19522, USA.

Brain Stimulation
|May 23, 2020
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Electrical fieldElectroconvulsive therapyMRINeurogenesisNeuroplasticityVolumetric change

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Electroconvulsive Therapy01:30

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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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