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Related Experiment Video

Updated: Dec 20, 2025

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

Paediatric aortic valve replacement using decellularized allografts.

Alexander Horke¹, Dmitry Bobylev¹, Murat Avsar¹

¹Department for Cardiothoracic, Transplant, and Vascular Surgery, Hannover Medical School, Hannover, Germany.

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery

|May 23, 2020

Summary

This summary is machine-generated.

Decellularized aortic homografts (DAHs) offer a promising new option for pediatric aortic valve replacement when repair is not possible. These grafts show excellent short-term results and potentially fewer complications than other procedures.

Area of Science:

Cardiovascular Surgery
Biomaterials Science
Pediatric Cardiology

Background:

Limited options exist for pediatric aortic valve replacement (AVR) when valve repair is not feasible.

Keywords:

Allografts Aortic valve disease Children Decellularization

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The Ross procedure has inferior outcomes in children compared to adults.

Mechanical AVR requires lifelong anticoagulation with associated risks.