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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
Synthesis, Redox Properties and Antibacterial Activity of Hindered Phenols Linked to Heterocycles
Vladimir N Koshelev1, Olga V Primerova1, Stepan V Vorobyev1
1Department of organic chemistry and petroleum chemistry, Gubkin Russian State University of Oil and Gas, Leninsky av. 65, 119991 Moscow, Russia.
Abstract:
A series of benzotriazole, cyclic amides and pyrimidine derivatives, containing 2,6-di-tert-butyl-phenol fragments, were synthesized. The redox properties of obtained compounds were studied using the cyclic voltammetry on a platinum electrode in acetonitrile. The oxidation potentials of all substances were comparable to those of BHT. The obtained compounds were tested for their antibacterial activity, and N-(2-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-oxoethyl)isatin (32 μg/mL) exerted good activity against Staphylococcus aureus.
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