Related Experiment Video
Updated: Dec 20, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Does this patient have COVID-19? A practical guide for the internist.
Lorenzo Bertolino1, Martina Vitrone1, Emanuele Durante-Mangoni2,3
1Department of Precision Medicine, Section of Internal Medicine, University of Campania 'L. Vanvitelli', Napoli, Italy.
Recognizing Coronavirus disease 2019 (COVID-19) requires internists to develop specific skills for differential diagnosis. Understanding the disease
Area of Science:
- Internal Medicine
- Infectious Diseases
- Clinical Diagnosis
Background:
- Coronavirus disease 2019 (COVID-19) presents a significant diagnostic challenge for physicians, particularly in differentiating it from other respiratory illnesses.
- The ongoing pandemic necessitates improved clinical approaches to accurately identify COVID-19 cases.
Purpose of the Study:
- To review key clinical features aiding in the differentiation of COVID-19 from other upper respiratory and influenza-like illnesses.
- To provide guidance for internists on recognizing COVID-19 in both outpatient and inpatient settings.
Main Methods:
- Review of clinical features and natural history of COVID-19.
- Consideration of diagnostic strategies in different clinical settings (outpatient vs. inpatient).
Main Results:
- COVID-19 often lacks specific signs and symptoms, making clinical diagnosis difficult.
- Knowledge of the disease's natural history can help contextualize common, unspecific symptoms.
Conclusions:
- Developing specific skills in recognizing COVID-19's 'semeiotic' is crucial for internists.
- A balanced clinical approach, informed by disease knowledge, is essential for managing patients with flu-like symptoms.
Related Concept Videos
Pneumonia III: Complications and Assessment
Myocarditis II: Clinical Features and Diagnostic Tests
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Pericarditis II: Clinical Features and Diagnostic Tests
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...

