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Published on: September 13, 2014
In situ skeletonized gastroepiploic artery grafting in hemodialysis patients
Kohei Hachiro1, Takeshi Kinoshita2, Tomoaki Suzuki1
1Division of Cardiovascular Surgery, Department of Surgery, Shiga University of Medical Science, Setatsukinowa, Otsu, Shiga, 520-2192, Japan.
Insights
Coronary artery bypass grafting in hemodialysis patients using the gastroepiploic artery showed acceptable short-term outcomes. This approach may be a viable option for patients with limited conduit availability.
Area of Science:
- Cardiovascular Surgery
- Nephrology
- Vascular Grafting
Background:
- Coronary artery bypass grafting (CABG) strategies for hemodialysis patients lack standardization.
- The gastroepiploic artery is a potential conduit for CABG, particularly in patients with limited options.
Purpose of the Study:
- To investigate the postoperative outcomes of isolated CABG using the in situ skeletonized gastroepiploic artery in hemodialysis patients.
- To evaluate the safety and efficacy of this surgical approach.
Main Methods:
- Retrospective analysis of 49 hemodialysis patients who underwent isolated CABG with gastroepiploic artery grafting between 2002 and 2019.
- Assessment of perioperative outcomes, including conversion rates, distal and proximal anastomoses, 30-day mortality, and early graft patency.
Main Results:
- No conversions from off-pump to on-pump surgery were required.
- The mean number of distal anastomoses was 3.6 per patient.
- Thirty-day mortality was 4.1%, and the early patency rate of the gastroepiploic artery was 96.9%.
- Survival rates free from death at 1, 5, and 10 years were 91.7%, 72.6%, and 32.5%, respectively.
- Age and left ventricular ejection fraction <40% were independent predictors of mid-term mortality.
Conclusions:
- The use of the in situ skeletonized gastroepiploic artery in CABG for hemodialysis patients yielded acceptable short- and mid-term outcomes.
- This technique may reduce aortic manipulation time and represents an important option for CABG in hemodialysis patients with limited conduit availability.
Objectives:
There is no firm treatment strategy of coronary artery bypass grafting in hemodialysis patients. We investigated postoperative outcomes in hemodialysis patients undergoing isolated coronary artery bypass grafting using in situ skeletonized gastroepiploic artery.
Methods:
From January 2002 to December 2019, 143 hemodialysis patients underwent isolated coronary artery bypass grafting in our institution. Among them, 49 consecutive patients with gastroepiploic artery grafting were retrospectively analyzed.
Results:
No patient was converted from off-pump to on-pump surgery. The mean distal anastomoses were 3.6 ± 1.0 per patients. Seven patients (14.3%) required proximal anastomosis to aorta. Thirty-day mortality was 4.1% (2 of 49). The early (3-20 days after surgery) patency rate of the gastroepiploic artery was 96.9% (63 of 65 anastomoses). The adjusted rates of survival free from overall death at 1, 5 and 10 years after surgery were 91.7%, 72.6% and 32.5%, respectively. Multivariate Cox proportional hazard regression analysis showed that age (hazard ratio 1.131, 95% confidence interval 1.055-1.212, p < 0.001) and LVEF < 40% (hazard ratio 9.411, 95% confidence interval 1.963-45.919, p = 0.005) were independent predictors of mid-term death from all causes (Table 6).
Conclusions:
Short and mid-term outcomes were acceptable. The use of in situ skeletonized gastroepiploic artery can decrease the time of touching aorta, so gastroepiploic artery grafting may be an important option for coronary artery bypass grafting in hemodialysis patients with limited conduits.
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Hemodialysis II: Procedure and Complications

