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AACC Guidance Document on Biotin Interference in Laboratory Tests.

Danni Li¹, Angela Ferguson², Mark A Cervinski³

¹Department of Lab Medicine and Pathology, University of Minnesota Medical Center, Minneapolis, MN.

The Journal of Applied Laboratory Medicine

|May 24, 2020

Summary

This summary is machine-generated.

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High biotin supplement intake can interfere with laboratory tests using biotin-streptavidin technology. This can cause inaccurate results in biotinylated immunoassays, necessitating awareness and proper identification strategies for accurate clinical diagnosis.

Area of Science:

Clinical Chemistry
Biochemistry
Laboratory Medicine

Background:

High biotin supplement consumption is increasing for cosmetic and health reasons.
Biotin interference affects laboratory tests utilizing streptavidin-biotin binding mechanisms.
This interference can lead to inaccurate results in biotinylated immunoassays.

Keywords:

Biotin Biotin Interference Immunoassay Interference

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