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Production of integrin αIIbβ3 in stably transfected and clonal Chinese hamster ovary cells for functional and

Li Pan1, Ying Lu2, Yongmei Zuo3

  • 1College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China.

Acta Biochimica Et Biophysica Sinica
|May 24, 2020
PubMed
Abstract

No abstract available in PubMed .

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Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
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