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Drug Therapy01:28

Drug Therapy

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The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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The discharge summary is crucial as it enables a smooth transition from a healthcare facility to a patient's home or another care setting. This critical document facilitates seamless continuity of care, ensuring patients receive the necessary support and attention.
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Acute Coronary Syndrome IV: Interprofessional Care01:28

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IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
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Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
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Heart Failure V: Medical Management01:30

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Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
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Therapeutic Drug Monitoring: Affecting Factors01:29

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Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
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Effect of Inpatient Medication-Assisted Therapy on Against-Medical-Advice Discharge and Readmission Rates.

Sijie Jason Wang1, Elizabeth Wade2, Jennifer Towle3

  • 1Department of Hospital Medicine.

The American Journal of Medicine
|May 24, 2020
PubMed
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Medication-assisted therapy (MAT) for hospitalized patients with infectious complications from intravenous opioid use significantly reduced against-medical-advice discharges and readmissions. Ongoing MAT at discharge further improved patient outcomes.

Keywords:
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Area of Science:

  • Addiction Medicine
  • Infectious Diseases
  • Hospital Medicine

Background:

  • Patients with infectious complications from intravenous opioid use face high risks of against-medical-advice discharge and readmissions.
  • The effectiveness of inpatient medication-assisted treatment (MAT) for opioid use disorder (OUD) remains unclear.

Purpose of the Study:

  • To assess outcomes before and after implementing an inpatient buprenorphine-based OUD protocol.
  • To evaluate the general impact of MAT on patient outcomes.

Main Methods:

  • Retrospective observational cohort study at a community hospital.
  • Inpatients with infectious complications of intravenous opioid use were identified.
  • Data were collected for admissions 11 months before and after the November 2018 buprenorphine protocol rollout.

Main Results:

  • MAT usage and buprenorphine linkage increased post-protocol implementation.
  • Against-medical-advice discharge and readmission rates did not decrease immediately after the protocol rollout.
  • However, overall, MAT was associated with substantially lower rates of against-medical-advice discharge (30.0% vs 59.6%) and reduced 30- and 90-day readmissions (all-cause and opioid-related) compared to supportive care only.

Conclusions:

  • A strong association exists between MAT and reduced against-medical-advice discharge rates.
  • Maintenance MAT at discharge is strongly linked to decreased readmission rates for patients with OUD.