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Updated: Dec 20, 2025

An Electrophysiology Protocol to Measure Reward Anticipation and Processing in Children
Published on: October 4, 2018
Initial Responsiveness to Reward Attainment and Psychopathology in Children and Adults: An RDoC Study
Avery B Albert1, Kayla E Wagner1, Sarah E Van Orman2
1Department of Psychiatry and Behavioral Sciences and of Neuroscience and Physiology, State University of New York - Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, U.S.A; Department of Psychology, Syracuse University, 430 Huntington Hall, Syracuse, New York 13244, U.S.A.
Abstract:
The Research Domain Criteria (RDoC) initiative of the National Institute of Mental Health (NIMH) established a dimensional framework for understanding psychiatric constructs. Initial Responsiveness to Reward Attainment (IRRA) was identified as a dimensional construct relevant to several psychiatric disorders. The current study aimed to (1) examine IRRA as a predictor of psychopathology and impairment in children and their parents, and (2) examine the potential effects of sex and ancestry on the relationship between IRRA and psychopathology. Participants included 1127 children ages 6 to 12, and 1018 of their parents. Parents and children completed self-report measures of IRRA. Psychopathology and impairment were measured using self-report for adults, and parent-report and semi-structured interview for children. In adults, IRRA was significantly, but modestly, related to adaptive functioning. In children, IRRA was significantly, but modestly, related to overall, school, spare time, home, and peer functioning. Findings suggest IRRA may be a helpful construct for understanding adaptive functioning in adults and children, however it may be less helpful for understanding specific dimensions of psychopathology. Additionally, ancestry should be taken into consideration when examining how IRRA relates to psychopathology and functioning.
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