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Isolation and identification of an anti-inflammatory principle from Capparis spinosa
M S al-Said1, E A Abdelsattar, S I Khalifa
1Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Die Pharmazie
|September 1, 1988
Abstract:
The homologous polyprenols cappaprenol-12 (1), cappaprenol-13 (2) and cappaprenol-14 (3) with 12, 13 and 14 isoprene units, respectively, could be isolated by preparative HPLC from alcoholic extracts of Capparis spinosa. Testing 2 for its anti-inflammatory activity an inhibition of the carrageenan-induced paw edema in rats of 44 vs. 67% for the standard oxyphenbutazone was found.