Exergames for balance dysfunction in neurological disability: a meta-analysis with meta-regression

Area of Science:

• Neurology
• Rehabilitation Medicine
• Digital Health

Background:

• Balance dysfunction is a significant challenge in various neurological conditions.
• Exergames offer a novel, engaging approach to physical rehabilitation.

Purpose of the Study:

• To systematically evaluate the efficacy of exergames for balance improvement in neurological disorders.
• To identify key factors within exergaming protocols that influence treatment outcomes.

Main Methods:

• Systematic review and meta-analysis of randomized clinical trials.
• Inclusion of studies on commercial exergames versus alternative interventions for balance dysfunction.
• Calculation of pooled effect sizes (Hedge's g) and subgroup/meta-regression analyses to explore effect modifiers.

Main Results:

• 41 studies with 1223 patients (stroke, Parkinson's, MS, etc.) were included.
• Exergames demonstrated a moderate positive effect on balance (g = 0.43, p < 0.001).
• Higher frequency of sessions per week was associated with significantly larger effect sizes (β = 0.24, p = 0.01).

Conclusions:

• Exergames are effective and safe for improving balance in individuals with neurological conditions.
• High-frequency exergaming protocols may optimize treatment outcomes.
• Potential for sustained balance improvements warrants further investigation.