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Updated: Dec 20, 2025

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Initial outcomes of a multidisciplinary network for the care of patients with cardiogenic shock
Francisco José Hernández-Pérez1, José Manuel Álvarez-Avelló2, Alberto Forteza3
1Servicio de Cardiología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain.
Insights
A multidisciplinary team and regional network for cardiogenic shock (CS) patients requiring mechanical circulatory support (MCS) is feasible. This program improved survival to discharge for over half of these critically ill patients.
Area of Science:
- Cardiology
- Critical Care Medicine
- Cardiovascular Surgery
Background:
- Cardiogenic shock (CS) has high mortality, particularly refractory CS requiring mechanical circulatory support (MCS).
- Establishing specialized care programs and regional networks is crucial for managing complex CS cases.
Purpose of the Study:
- To evaluate the outcomes of a dedicated care program for CS patients.
- To assess the impact of a multidisciplinary team and regional network on patient survival.
Main Methods:
- Retrospective observational study of 130 CS patients (Sept 2014 - Jan 2019).
- Included patients with refractory CS requiring MCS and those eligible for advanced therapies.
- Primary endpoint: survival to discharge.
Main Results:
- Overall survival to discharge was 57% (74/130 patients).
- Mechanical circulatory support (MCS) was used in 81% of patients, primarily extracorporeal membrane oxygenation.
- Independent predictors of mortality included SAPS II score, lactate level, acute myocardial infarction, and vasoactive-inotropic score.
Conclusions:
- A multidisciplinary team approach and regional network for CS patients are feasible.
- This integrated care model significantly improves survival to discharge rates in critically ill CS patients.
Introduction And Objectives:
Mortality remains high in cardiogenic shock (CS), especially in refractory CS involving the use of mechanical circulatory support (MCS) devices. The aim of this study was to analyze the results of a care program for patients in CS after the creation of a multidisciplinary team in our center and a regional network of hospitals in our area.
Methods:
Observational and retrospective study of patients attended in this program from September 2014 to January 2019. We included patients in refractory CS who required MCS and those who, because of their age and absence of comorbidities, were candidates for advanced therapies. The primary endpoint was survival to discharge.
Results:
A total of 130 patients were included (69 local and 61 transferred patients). The mean age was 52±15 years (72% men). The most frequent causes of CS were acute decompensated heart failure (29%), acute myocardial infarction (26%), and postcardiotomy CS (25%). MCS was used in 105 patients (81%), mostly extracorporeal membrane oxygenation (58%). Survival to discharge was 57% (74 of 130 patients). The most frequent destinations were myocardial recovery and heart transplant. Independent predictors of in-hospital mortality were SAPS II score, lactate level, acute myocardial infarction etiology, and vasoactive-inotropic score.
Conclusions:
The creation of multidisciplinary teams for patients with mainly refractory CS and a regional network is feasible and allows survival to discharge in more than a half of attended patients with CS.
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