Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bismuth is better.

G N Tytgat1

  • 1Dept. of Medicine, University of Amsterdam, The Netherlands.

Scandinavian Journal of Gastroenterology. Supplement
|January 1, 1988
PubMed
Summary

Colloidal bismuth subcitrate (CBS) effectively heals peptic ulcers without altering stomach acidity. Healing rates match H2-receptor antagonists (HRA), with potentially lower and delayed relapse rates after CBS treatment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Piperacillin to prevent cholangitis after endoscopic retrograde cholangiopancreatography. A randomized, controlled trial.

Annals of internal medicine·1996
Same author

Heterogeneous Helicobacter pylori isolates from members of a family with a history of peptic ulcer disease.

Gastroenterology·1996
Same author

Effects of Ursodeoxycholate and cholate feeding on liver disease in FVB mice with a disrupted mdr2 P-glycoprotein gene.

Gastroenterology·1996
Same author

The endoscopic assessment of esophagitis: a progress report on observer agreement.

Gastroenterology·1996
Same author

Mechanism of bile salt-induced mucin secretion by cultured dog gallbladder epithelial cells.

The Biochemical journal·1996
Same author

Correlation between early recurrence and reoperation after ileocolonic resection in Crohn's disease: a prospective study.

Journal of the American College of Surgeons·1996

Area of Science:

  • Gastroenterology
  • Pharmacology

Background:

  • Peptic ulcer healing traditionally involves drugs that reduce intragastric acidity.
  • Limited options exist for ulcer treatments that do not interfere with stomach acid levels.

Purpose of the Study:

  • To evaluate the efficacy of colloidal bismuth subcitrate (CBS) in healing peptic ulcers.
  • To compare CBS healing rates and relapse patterns with established H2-receptor antagonists (HRA).

Main Methods:

  • Clinical assessment of peptic ulcer healing rates.
  • Comparison of outcomes between colloidal bismuth subcitrate and H2-receptor antagonists.

Main Results:

  • Colloidal bismuth subcitrate (CBS) demonstrated effective healing for both duodenal and gastric ulcers.
  • Healing rates achieved with CBS were comparable to those of H2-receptor antagonists (HRA).
  • Relapse rates following CBS treatment appeared lower and delayed compared to HRA treatment.

Conclusions:

  • Colloidal bismuth subcitrate (CBS) offers a viable therapeutic option for peptic ulcer healing.
  • CBS provides comparable efficacy to H2-receptor antagonists (HRA) without affecting intragastric acidity.
  • CBS may offer a superior long-term outcome regarding ulcer relapse.

Related Experiment Videos