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Updated: Dec 20, 2025
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RBDT: A Computerized Task System based in Transposition for the Continuous Analysis of Relational Behavior Dynamics in Humans
Published on: July 17, 2021
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Anatomical Studies of Transposition - An Argument for a Unifying Morphological Classification
Nikita Maria1, Max E Roderick1, John Stickley2
1Department of Paediatric Cardiac Surgery, Birmingham Children's Hospital, Birmingham, United Kingdom; Institute of Clinical Sciences, University of Birmingham, Birmingham, United Kingdom.
Seminars in Thoracic and Cardiovascular Surgery
|May 26, 2020
Summary
Recognizing anatomical variations in transposition is crucial for surgical repair. A unified classification system for these heart defects can reduce misunderstandings and improve patient outcomes.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Congenital Heart Disease
Background:
- Surgical repair of transposition requires understanding outflow tract and arterial trunk morphology.
- Current terminology can be ambiguous, leading to potential misunderstandings in clinical practice.
Purpose of the Study:
- To analyze the morphological variability in transposition.
- To propose a more precise descriptive approach for classification.
Main Methods:
- Retrospective analysis of 142 unrepaired hearts with transposition.
- Review of clinical records from 727 patients undergoing arterial switch procedures.
Main Results:
- The term "d-transposition" is ambiguous due to aortic root location variability (up to 5%).
- Arterial trunk relationship variability is more common with deficient ventricular septation (14% vs 5.5%).
- Bilateral infundibulums and deficient infundibulums were more frequent in hearts with deficient ventricular septation.
Conclusions:
- Transposition, defined by concordant atrioventricular and discordant ventriculoarterial connections, requires precise description of atrial arrangement and arterial trunk relationships.
- A unified classification system for transpositional defects is needed to minimize surgical risks.
- Fibrous continuity between tricuspid and mitral valves is a key feature of perimembranous defects.
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