Related Experiment Video
Updated: Dec 20, 2025

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Fibrosing Mediastinitis Requiring Multimodality Treatment to Maintain Pulmonary Vein Patency
Paul Jennings1, Joanna Sesti2, Amber L Turner3
1Department of Thoracic Surgery, RWJBarnabas Health, Newark Beth Israel Medical Center, Newark, New Jersey.
Abstract:
Fibrosing mediastinitis is a rare condition with limited epidemiologic data. We detail a case of a 43-year-old female with no past medical history, who presented with chest pain and dyspnea on exertion. Chest computed tomography revealed a large mediastinal mass that was invading into the anterior chest as well as encasing the pulmonary hilum. Surgical pathology returned as dense hyaline fibrosis tissue with focal histiocytic aggregates and giant cells consistent with fibrosing mediastinitis. Treatment with rituximab and steroids showed a reduction in the size of her mass.
Related Concept Videos
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Pulmonary Embolism III: Nursing Management
Mitral Stenosis III: Medical Management
Venous Thrombosis III: Interprofessional Care
Pneumothorax-II
Clinical Manifestations:
Flail Chest-II
Assessment:
1. Clinical Evaluation:
History:

