Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

290
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
290
Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

947
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
947
Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

110
Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
110

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prospective validation of the EASL-EASD algorithm for risk stratification in patients with metabolic dysfunction-associated steatotic liver disease and type 2 diabetes.

Revista espanola de enfermedades digestivas·2025
Same author

Endovascularly Treatable Causes of Hemoptysis: Guide for Emergency Radiologists.

Radiographics : a review publication of the Radiological Society of North America, Inc·2025
Same author

Acute acalculous cholecystitis secondary to hepatitis A infection.

Revista espanola de enfermedades digestivas·2024
Same author

Low phospholipid-associated cholelithiasis syndrome, a not uncommon cause of biliary problems and hospital admissions.

Revista espanola de enfermedades digestivas·2024
Same author

Protocol for acquisition of images and measurement of transabdominal ultrasound pancreatic two-dimensional shear wave elastography (2D-SWE).

Gastroenterologia y hepatologia·2024
Same author

Whipple's disease in the elderly.

Gastroenterologia y hepatologia·2023

Related Experiment Video

Updated: Dec 20, 2025

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy
07:10

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy

Published on: June 18, 2020

22.2K

Hemodynamic changes after endoscopic variceal ligation: a cohort study.

Nerea Gonzalo Bada1, José Manuel Suárez Parga1, Teresa Hernández Cabrero2

  • 1Aparato Digestivo, Hospital Universitario La Paz, ESPAÑA.

Revista Espanola De Enfermedades Digestivas
|May 27, 2020
PubMed
Summary

Endoscopic band ligation (EBL) for bleeding esophageal varices (BEV) significantly increases hepatic venous pressure gradient (HVPG), indicating a rise in portal pressure. This hemodynamic change, measured 24 hours post-ligation, highlights a potential need for adjusted management strategies.

More Related Videos

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
04:09

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Published on: June 13, 2025

777
Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices
02:14

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices

Published on: August 1, 2025

1.1K

Related Experiment Videos

Last Updated: Dec 20, 2025

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy
07:10

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy

Published on: June 18, 2020

22.2K
Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
04:09

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Published on: June 13, 2025

777
Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices
02:14

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices

Published on: August 1, 2025

1.1K

Area of Science:

  • Hepatology
  • Gastroenterology
  • Hemodynamics

Background:

  • Controversy exists regarding the necessity of continued vasoconstrictor therapy after successful endoscopic band ligation (EBL) for bleeding esophageal varices (BEV).
  • Measuring hepatic venous pressure gradient (HVPG) before and after urgent EBL in acute variceal hemorrhage is clinically challenging.
  • This study aimed to assess hemodynamic variations following EBL sessions in patients with cirrhotic varices.

Purpose of the Study:

  • To determine the hemodynamic changes, specifically portal pressure variations, after endoscopic band ligation (EBL) in patients with bleeding esophageal varices (BEV).
  • To evaluate the impact of EBL on the hepatic venous pressure gradient (HVPG) in cirrhotic patients undergoing treatment for esophageal varices.

Main Methods:

  • A prospective, single-center cohort study was conducted.
  • Hepatic venous pressure gradient (HVPG) was measured before (PRE) and 24 hours after (POST) endoscopic band ligation (EBL) sessions.
  • Patients with esophageal varices, undergoing EBL for prophylaxis, continued their usual beta-blocker treatment throughout the study.

Main Results:

  • Thirty patients were included in the study.
  • A statistically significant increase in HVPG was observed, with median PRE HVPG of 16.5 mmHg rising to 19.5 mmHg POST (p < 0.001).
  • A notable percentage increase in portal pressure (≥ 20%) occurred in 36.7% of patients, with greater relative increases seen in those with lower baseline HVPG.

Conclusions:

  • Endoscopic band ligation (EBL) demonstrably increases portal pressure, as evidenced by changes in the hepatic venous pressure gradient (HVPG).
  • This elevation in portal pressure following EBL appears to be a transitional hemodynamic effect.
  • The findings suggest that the hemodynamic impact of EBL on portal pressure warrants consideration in the management of bleeding esophageal varices.