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Updated: Dec 20, 2025

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
Published on: May 26, 2023
Surgical Field Visualization during Functional Endoscopic Sinus Surgery: Comparison of Propofol- vs Desflurane-Based
Suneeta Gollapudy1, Drake A Gashkoff2, David M Poetker3,4
1Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
For endoscopic sinus surgery, propofol offers no visual field advantage over desflurane when remifentanil is used for controlled hypotension. This study found no significant differences in bleeding or visualization between anesthetic types.
Area of Science:
- Otolaryngology
- Anesthesiology
- Surgical Innovation
Background:
- Endoscopic sinus surgery (ESS) requires clear visualization, which can be impacted by bleeding.
- Anesthetic choice may influence bleeding and surgical field quality during ESS.
Purpose of the Study:
- To compare the effects of desflurane, propofol, and a combination anesthetic on bleeding and surgical field visualization during ESS.
Main Methods:
- A prospective, randomized controlled trial involving 70 patients undergoing ESS.
- Patients were assigned to desflurane, propofol, or a combination anesthetic, with remifentanil used for controlled hypotension.
- Bleeding scores, rates, and hemodynamic parameters were recorded.
Main Results:
- No significant differences were observed in bleeding rates, bleeding scores, surgery duration, or hemodynamic parameters among the three anesthetic groups.
- The desflurane group required lower remifentanil infusion rates compared to the propofol group.
- Bleeding score correlated with patient height and Lund-MacKay score; bilateral surgeries prolonged operating time.
Conclusions:
- Propofol does not provide an advantage over desflurane for improving surgical field visualization in ESS when controlled hypotension is achieved with remifentanil.
- Anesthetic selection may not be a primary determinant of surgical field quality in this context.
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