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Coronavirus Disease-2019 (COVID-19) and Cardiovascular Complications
Lulu Ma1, Kaicheng Song1, Yuguang Huang1
1Department of Anesthesiology, Peking Union Medical College Hospital, Beijing, China.
Insights
Coronavirus disease 2019 (COVID-19) can cause severe cardiac complications, especially in patients with pre-existing cardiovascular disease. Early identification and supportive care are crucial for managing COVID-19 patients at high risk for heart problems.
Area of Science:
- Infectious Diseases
- Cardiology
- Public Health
Background:
- Coronavirus disease 2019 (COVID-19) is a global pandemic with significant health implications.
- While primarily a respiratory illness, COVID-19 is increasingly linked to cardiac complications.
- Patients with underlying cardiovascular disease are particularly vulnerable to adverse outcomes.
Purpose of the Study:
- To review the fundamentals of the virus causing COVID-19.
- To outline the clinical manifestations of COVID-19, focusing on cardiac involvement.
- To explore potential mechanisms underlying cardiac complications in COVID-19 patients.
Main Methods:
- Literature review of existing data on COVID-19 and cardiovascular disease.
- Analysis of clinical presentations and outcomes in affected patients.
- Synthesis of current understanding regarding viral impact on the cardiovascular system.
Main Results:
- COVID-19 can lead to significant cardiac complications, impacting patient outcomes.
- A substantial proportion of COVID-19 patients have pre-existing cardiovascular conditions, increasing their risk.
- Understanding the virus, its manifestations, and mechanisms of cardiac injury is essential.
Conclusions:
- Supportive therapy is vital for managing COVID-19, particularly in high-risk cardiac patients.
- Identifying patients prone to cardiac complications is a critical aspect of care.
- Further research into the cardiovascular impact of COVID-19 is warranted pending vaccine or therapeutic availability.
Abstract:
The coronavirus disease-2019 (COVID-19) has become a global pandemic. It has spread to more than 100 countries, and more than 1 million cases have been confirmed. Although coronavirus causes severe respiratory infections in humans, accumulating data have demonstrated cardiac complications and poor outcome in patients with COVID-19. A large percent of patients have underlying cardiovascular disease, and they are at a high risk of developing cardiac complications. The basics of the virus, the clinical manifestations, and the possible mechanisms of cardiac complications in patients with COVID-19 are reviewed. Before an effective vaccine or medicine is available, supportive therapy and identifying patients who are at high risk of cardiac complications are important.
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