Related Experiment Video

Updated: Dec 20, 2025

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
07:51

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

7.9K

Do underlying cardiovascular diseases have any impact on hospitalised patients with COVID-19?

Jixiang Zhang1, Shimin Lu1, Xiaoli Wang2

  • 1Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.

Heart (British Cardiac Society)
|May 27, 2020
PubMed

Insights

Patients with cardiovascular disease (CVD) face a higher risk of severe outcomes and mortality from COVID-19. Early assessment and intervention for CVD are crucial in managing these vulnerable patients.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Critical Care Medicine

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, has led to a global health crisis.
  • Cardiovascular disease (CVD) is a common comorbidity, and its impact on COVID-19 prognosis is a critical area of investigation.

Purpose of the Study:

  • To investigate the early clinical characteristics of COVID-19 patients with pre-existing cardiovascular disease (CVD).
  • To identify associations between CVD and clinical outcomes in patients with COVID-19.

Main Methods:

  • Retrospective analysis of 541 COVID-19 patients from a single center.
  • Real-time reverse transcription PCR confirmed SARS-CoV-2 infection.
  • Demographic, clinical, and laboratory data were collected and analyzed for significant associations.

Main Results:

  • 144 patients (26.6%) had a history of CVD, with a significantly higher mortality rate (22.2%) compared to non-CVD patients (9.8%).
  • CVD patients exhibited higher rates of liver dysfunction, elevated creatinine, and lactic dehydrogenase, along with more sputum production.
  • Critically ill patients were more prevalent in the CVD group (27.8% vs. 8.8%), and CVD was independently associated with critical illness (OR: 2.735).

Conclusions:

  • COVID-19 patients with CVD demonstrate increased vulnerability to severe disease and poorer outcomes.
  • Thorough cardiovascular assessment and prompt intervention are recommended for COVID-19 patients diagnosed with CVD.
  • Coronary heart disease was associated with a lower likelihood of recovery.
Abstract

Keywords:
cardiac rehabilitationcardiac risk factors and preventionelectronic medical recordshypertension

More Related Videos

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control05:41

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

4.2K
Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure05:16

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

460

Related Concept Videos

Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
239
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
270
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
778
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
2.1K
Cardiovascular Drugs: Classification based on Therapeutic Indications01:18

Cardiovascular Drugs: Classification based on Therapeutic Indications

Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However,...
3.9K
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
115