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Localized Amyloidosis Involving Palatine Tonsils: A Case Report and Literature Review
S E Schmid1, N B Nesbitt2, A N Snitchler3
1U.S. Army Medical Center of Excellence, San Antonio, TX, USA.
Head and Neck Pathology
|May 27, 2020
Summary
This study reports a rare case of bilateral tonsillar amyloidosis in a 59-year-old male. Surgical resection was successful, highlighting a second documented instance of this localized amyloidosis presentation.
Area of Science:
- Otorhinolaryngology
- Pathology
- Oncology
Background:
- Amyloidosis involves extracellular deposition of insoluble protein fibers in tissues.
- Localized amyloidosis is rare but curable via surgical resection.
- The head and neck region accounts for 19% of localized amyloidosis cases.
Observation:
- A 59-year-old male presented with asymptomatic amyloidosis.
- The amyloidosis was isolated to bilateral palatine tonsils and a cervical lymph node.
- This represents the second reported case of bilateral tonsillar amyloidosis.
Findings:
- Multidisciplinary consultation ruled out systemic amyloidosis.
- Surgical resection of the affected tonsils and lymph node was performed.
- The patient's condition was successfully treated with localized intervention.
Implications:
- This case adds to the limited literature on bilateral tonsillar amyloidosis.
- Highlights the importance of considering localized amyloidosis in head and neck presentations.
- Emphasizes the curability of localized amyloidosis through prompt surgical management.
