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[Chemonucleolysis--with extended indications. 4 years clinical experience]
P R Bock-Lamberlin1, F W Rose, M Schwonbeck
1Orthopädische Universitätsklinik und Poliklinik Hamburg-Eppendorf.
Zeitschrift Fur Orthopadie Und Ihre Grenzgebiete
|December 1, 1988
Summary
Chemonucleolysis, a minimally invasive procedure, shows promising results even in cases previously considered contraindications, including spinal stenosis and reherniations after surgery. Repeat treatments are also viable, expanding treatment options for patients.
Area of Science:
- Minimally Invasive Spine Procedures
- Interventional Pain Management
- Spinal Disc Treatments
Context:
- Evaluation of chemonucleolysis outcomes in a large patient cohort (1141 patients, 1289 procedures).
- Assessment of patient-reported outcomes via questionnaire (80% response rate).
- Review of previously established contraindications for chemonucleolysis.
Purpose:
- To re-evaluate the efficacy and safety of chemonucleolysis in specific patient subgroups.
- To determine the feasibility of repeat chemonucleolysis procedures.
- To assess the potential of chemonucleolysis in post-surgical reherniation cases.
Summary:
- Chemonucleolysis demonstrates significant positive outcomes in patients with disk herniations and spinal stenosis.
- Repeat chemonucleolysis procedures using chymopapain are clinically feasible.
- Patients with reherniation after prior surgery can benefit from chemonucleolysis.
Impact:
- Challenges traditional contraindications for chemonucleolysis, broadening patient eligibility.
- Establishes repeat chemonucleolysis as a viable treatment option.
- Offers a potential therapeutic avenue for recurrent disk herniations post-surgery.