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Novel therapies for advanced urologic cancers
1Department of Urology, Urologic Oncology, Robot-Assisted and Specialized Urologic Surgery, University of Cologne, Cologne, Germany.
Current Opinion in Urology
|May 27, 2020
Summary
Recent advancements in urogenital cancer treatment include immunooncological therapy for renal cell carcinoma and new options for bladder, prostate, and testis cancers. These strategies are ready for routine clinical use.
Area of Science:
- Uro-oncology
- Medical oncology
- Cancer treatment
Background:
- Systemic treatment for advanced urogenital malignancies is rapidly evolving.
- Personalized treatment strategies are crucial for optimal patient outcomes.
Purpose of the Study:
- To review recently approved treatment strategies for advanced urogenital malignancies.
- To provide guidance on individualized patient treatment.
Main Methods:
- Review of recent clinical trials and therapeutic developments.
- Focus on immunooncological therapy (IOT), neoadjuvant treatments, and medical therapies for metastatic cancers.
Main Results:
- Immunooncological therapy is a primary treatment for metastatic renal cell carcinoma.
- New neoadjuvant options for muscle-invasive bladder cancer are available.
- Evolving landscape of therapies for metastatic hormone-naive and castration-resistant prostate cancer.
- Latest developments in advanced testis cancer management.
Conclusions:
- Novel treatment options are ready for routine clinical practice.
- These therapies are expected to become guideline-recommended treatments.
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