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Paediatric antimicrobial stewardship programmes in the UK's regional children's hospitals

S Vergnano1, A Bamford2, S Bandi3

  • 1University of Bristol, Bristol, UK; Bristol Royal Hospital for Children, Bristol, UK.

The Journal of Hospital Infection
|May 27, 2020
PubMed

Insights

This study surveyed UK children

Area of Science:

  • Pediatric Infectious Diseases
  • Antimicrobial Stewardship
  • Healthcare Management

Background:

  • Paediatric antimicrobial stewardship (PAS) programmes are crucial for optimizing antibiotic use in children.
  • Variations in PAS programme structures and practices exist across different hospital departments.
  • Understanding these characteristics is essential for improving antimicrobial resistance strategies.

Purpose of the Study:

  • To describe the characteristics of paediatric antimicrobial stewardship (PAS) programmes in UK regional children's hospitals.
  • To identify differences in PAS programme implementation between microbiology-led and paediatric infectious disease (PID)-led services.
  • To report on the establishment of a national PAS network.

Main Methods:

  • A structured questionnaire was distributed to PAS coordinators in UK children's hospitals.
  • Hospitals surveyed included those with paediatric intensive care and paediatric infectious disease departments.
  • Data were collected on programme structure, interventions, and patient review processes.

Main Results:

  • Audit and feedback was a common intervention, used in 13 out of 17 surveyed centres.
  • Microbiology-led services were more likely to implement antimicrobial restrictions (75% vs 33%) and focus on broad-spectrum antibiotics.
  • Paediatric infectious disease-led services demonstrated different review strategies, including using e-prescribing data.

Conclusions:

  • Significant variations exist in PAS programme characteristics based on departmental leadership (microbiology vs. PID).
  • The establishment of a PAS network facilitates collaboration and standardization of best practices.
  • Further research can optimize PAS programme design to combat antimicrobial resistance in pediatric populations.

Keywords:
Antimicrobial stewardshipChildrenPaediatricsProgramme implementation

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