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Carbon Quantum Dots: Synthesis, Characterization and Biomedical Applications.

Inderbir Singh1, Riya Arora1, Hardik Dhiman1

  • 1Chitkara University, Chitkara College of Pharmacy, Department of Pharmaceutics, Punjab, India.

Turkish Journal of Pharmaceutical Sciences
|May 27, 2020
PubMed
Summary

Carbon dots (CQDs), small nanoparticles under 10 nm, are vital for targeted delivery and biomedical research. This review consolidates their synthesis, characterization, and promising applications in bioimaging and drug delivery.

Keywords:
Carbon quantum dotscarbon dotsnanocompositesnanoparticlesphotoluminescencequantum yield

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Area of Science:

  • Nanotechnology
  • Biomedical Engineering
  • Materials Science

Background:

  • Carbon dots (CQDs) are nanoscale carbon particles (<10 nm) with unique properties.
  • They are increasingly utilized in targeted drug delivery, bioimaging, and therapeutic applications.
  • Understanding their synthesis and characterization is crucial for advancing biomedical research.

Purpose of the Study:

  • To review and consolidate current literature on CQD synthesis, characterization, and biomedical applications.
  • To highlight the progress and potential of CQDs in the biomedical field.
  • To provide a comprehensive overview for researchers in nanotechnology and medicine.

Main Methods:

  • Literature review of synthesis techniques for CQDs.
  • Analysis of characterization methods for CQDs.
  • Exploration of diverse biomedical applications, including bioimaging and drug delivery.

Main Results:

  • Two primary synthesis approaches exist: top-down (arc-discharge, laser ablation, electrochemical) and bottom-up (thermal, microwave, hydrothermal, template methods).
  • CQDs demonstrate significant potential for in vivo and in vitro bioimaging.
  • CQDs show extensive adequacy for drug delivery studies, with a bright future indicated.

Conclusions:

  • Carbon dots offer versatile properties for advanced biomedical applications.
  • Further cytotoxicity studies are necessary to fully realize their therapeutic potential.
  • CQDs are poised to become indispensable tools in targeted drug delivery and bioimaging.