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Parkinson's Disease: Treatment01:24

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Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
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Phytotherapy as a Complementary Medicine for Multiple Sclerosis.

Zahra Rabiei1

  • 1Shahrekord University of Medical Sciences, Basic Health Sciences Institute, Medical Plants Research Center, Shahrekord, Iran.

Turkish Journal of Pharmaceutical Sciences
|May 27, 2020
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Summary
This summary is machine-generated.

Medicinal plants show promise for managing multiple sclerosis (MS) symptoms. Extracts from plants like Cannabis sativa and Ginkgo biloba may reduce MS-related neurologic deficits and improve patient well-being.

Keywords:
medicinal plantsphytotherapyMultiple sclerosis

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Area of Science:

  • Neurology
  • Pharmacology
  • Botany

Background:

  • Multiple sclerosis (MS) is a leading cause of adult neurologic disability globally.
  • MS presents challenges due to undetermined etiology and lack of definitive treatments.
  • Patients often seek complementary and alternative medicine for symptom management.

Purpose of the Study:

  • To review the therapeutic potential of medicinal plants and their compounds for multiple sclerosis.
  • To identify specific plant-derived agents that may alleviate MS symptoms and neurologic deficits.

Main Methods:

  • Systematic literature search across major scientific databases (Web of Science, Scopus, PubMed, etc.).
  • Analysis of retrieved articles focusing on the effects of medicinal plants in MS models and patients.
  • Evaluation of clinical and preclinical evidence for plant-based interventions.

Main Results:

  • Medicinal plants and compounds demonstrated efficacy in reducing MS-related neurologic deficits.
  • Clinical evidence supports Cannabis sativa, Ginkgo biloba, and Lippia citriodora extracts for improving MS symptoms.
  • Specific agents like nanocurcumins and Punica granatum peel extract showed anti-inflammatory effects in animal models.

Conclusions:

  • Medicinal plants offer a promising avenue for novel therapeutic strategies in multiple sclerosis.
  • Plant-derived compounds can potentially alleviate key MS symptoms such as spasticity and pain.
  • Further research into these natural products could lead to new drug development for MS.