Related Experiment Video

Updated: Dec 20, 2025

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

10.4K

COVID-19 patients exhibit less pronounced immune suppression compared with bacterial septic shock patients

Matthijs Kox1,2, Tim Frenzel3,4, Jeroen Schouten3,4

  • 1Department of Intensive Care Medicine, Radboud University Medical Center, Internal Mail 710, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Matthijs.Kox@radboudumc.nl.

Critical Care (London, England)
|May 28, 2020
PubMed
Abstract

No abstract available in PubMed .

Keywords:
COVIDCOVID-19HLA-DRImmune suppressionMonocytesSARS-CoV-2mHLA-DR

More Related Videos

A Data-Driven Approach to Quantifying Immune States in Sepsis
07:42

A Data-Driven Approach to Quantifying Immune States in Sepsis

Published on: February 7, 2025

420
A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats
05:56

A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats

Published on: February 20, 2021

2.4K

Related Experiment Videos

Last Updated: Dec 20, 2025

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

10.4K
A Data-Driven Approach to Quantifying Immune States in Sepsis
07:42

A Data-Driven Approach to Quantifying Immune States in Sepsis

Published on: February 7, 2025

420
A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats
05:56

A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats

Published on: February 20, 2021

2.4K

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

13.1K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.1K
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

2.3K
The pathophysiology of pneumonia involves the following steps:
2.3K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

2.5K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
2.5K

Articles linked to this work by shared authors, journal, and citation graph.

Immunotherapy for invasive Candida infections: Translating host-directed strategies into clinical practice.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026

Translational modelling challenges receptor‑occupancy‑based dosing of PD‑1 inhibitors like pembrolizumab.

British journal of cancer·2026

Testing Knowledge Boundaries: Adversarial Evaluation of LLMs for Antimicrobial Stewardship.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026

Antimicrobial stewardship in practice: determinants of prescription behaviour and developing interventions to improve surgical prophylaxis in a Rwandan tertiary hospital-a mixed methods study using the behaviour change wheel.

Antimicrobial resistance and infection control·2026

Genetic variation in the long pentraxin PTX3 and Dectin-1 does not predispose to influenza- or COVID-19-associated pulmonary aspergillosis.

The Journal of infectious diseases·2026

Artificial intelligence and antimicrobial stewardship: From clinical decision support to public health action-On behalf of APUA.

Journal of global antimicrobial resistance·2026

Physiological limits of capillary refill time: a human endotoxemia study.

Critical care (London, England)·2026

Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy.

Critical care (London, England)·2026

Extracorporeal CO2 elimination for acute exacerbation of severe COPD requiring invasive mechanical ventilation: a randomized controlled trial (the X-COPD trial).

Critical care (London, England)·2026

Death determination at the bedside: clinical judgement beyond criteria.

Critical care (London, England)·2026

Left ventricular unloading during VA-ECMO for refractory cardiogenic shock: a target trial emulation multicenter analysis.

Critical care (London, England)·2026

Assessment of the effectiveness of protein in critical illness: the role of statistical shortcomings in explaining discrepancies between observational studies and randomized controlled trials.

Critical care (London, England)·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us