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Updated: Dec 20, 2025

Assembling Molecular Shuttles Powered by Reversibly Attached Kinesins
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Light-switchable propulsion of active particles with reversible interactions.

Hanumantha Rao Vutukuri1, Maciej Lisicki2, Eric Lauga3

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Researchers developed self-propelled Janus particles with switchable interactions. These active colloids can control assembly and disassembly, enabling dynamic material design.

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Area of Science:

  • Soft Matter Physics
  • Active Matter Systems
  • Nanotechnology

Background:

  • Microorganisms and self-propelled particles exhibit collective behaviors like swarming and clustering.
  • Controlling particle propulsion and interactions is key for designing novel materials.
  • Janus particles offer tunable properties due to their asymmetric surface coatings.

Purpose of the Study:

  • To present a novel self-propelled particle system with on-demand propulsion reversal.
  • To investigate the impact of reversed propulsion on inter-particle hydrodynamic interactions.
  • To demonstrate the potential for reconfigurable assembly and disassembly of active matter.

Main Methods:

  • Fabrication of half-gold-coated titania (TiO2) Janus particles.
  • Utilizing differential photocatalytic activity to control propulsion direction.
  • Observing particle dynamics and assembly transitions using microscopy.
  • Employing a minimal hydrodynamic model for qualitative description.

Main Results:

  • Achieved rapid, on-demand reversal of particle propulsion direction.
  • Demonstrated the switch from attractive to repulsive hydrodynamic interactions upon propulsion reversal.
  • Observed fusion and fission transitions in particle assemblies.
  • Showcased active colloids acting as nucleation sites for reconfigurable assembly.

Conclusions:

  • The developed Janus particle system allows for dynamic control over active matter behavior.
  • Switchable interactions enable tunable fusion, fission, and reconfigurable assembly.
  • This platform offers new possibilities for designing responsive and self-assembling materials.