Related Experiment Video
Updated: Dec 20, 2025
08:03
Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
Published on: December 7, 2021
2.7K
How Can We Not Waste Legacy Genomic Research Data?
Susan E Wallace1, Emily Kirby2, Bartha Maria Knoppers2
1Department of Health Sciences, University of Leicester, Leicester, United Kingdom.
Frontiers in Genetics
|May 28, 2020
Summary
Researchers can now determine how to share legacy genomic and biomedical data for secondary research. A new filter helps assess data sharing compliance and identify necessary actions, preventing valuable research from being underutilized.
Area of Science:
- Genomics
- Biomedical Research
- Data Science
Background:
- Sharing legacy genomic and biomedical data for secondary research presents ethical and regulatory challenges.
- Underutilization of publicly funded research data limits scientific advancement.
- Current data sharing practices often fail to meet requirements for legacy datasets.
Purpose of the Study:
- To introduce a novel filter designed to assist researchers in evaluating the shareability of legacy data.
- To provide actionable steps for enhancing data sharing compliance for existing datasets.
- To promote the secondary use of valuable biomedical and genomic research data.
Main Methods:
- Development of a data sharing compliance filter through the Global Alliance for Genomics and Health driver projects.
- Evaluation of the filter's utility in assessing legacy data for secondary research purposes.
Main Results:
- The developed filter provides a clear framework for researchers to understand data sharing limitations.
- The filter identifies specific actions required to enable broader data sharing.
- Facilitates the secondary use of valuable research data.
Conclusions:
- The filter offers a practical solution to overcome barriers in sharing legacy genomic and biomedical data.
- Implementing this tool can maximize the impact of research investments and accelerate scientific discovery.
- Encourages a move away from "single-use" research data.
Related Concept Videos
02:54Evolutionary Relationships through Genome Comparisons
6.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
6.7K
02:02Genomics
39.4K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
39.4K
03:00Next-generation Sequencing
97.2K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
97.2K