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EORTC QLU-C10D value sets for Austria, Italy, and Poland.

E M Gamper¹, M T King², R Norman³

¹Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital Psychiatry II, Medical University of Innsbruck, Innsbruck, Austria. eva-maria.gamper@i-med.ac.at.

Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation

|May 28, 2020

Summary

New cancer utility values (QLU-C10D) are available for Austria, Italy, and Poland. These country-specific values are crucial for accurate economic evaluations in cancer care, reflecting distinct health state preferences.

Keywords:

Austria Cancer-specific Discrete choice experiment EORTC QLQ-C30 EORTC QLU-C10D Health utilities Italy Poland

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Area of Science:

Health Economics
Psychometrics
Oncology

Background:

The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) is a widely used cancer-specific instrument.
Developing country-specific utility values for cancer patients enhances the accuracy of health economic evaluations.

Purpose of the Study:

To establish general population value sets for the EORTC QLU-C10D in Austria, Italy, and Poland.
To compare the index scores for various health states across these three countries.

Main Methods:

A web-based discrete choice experiment (DCE) was employed, assessing 10 health attributes each with 4 levels.
The study included 1000 general population respondents per country, recruited via online panels for representativeness.
A standardized and pre-tested valuation methodology was applied.

Main Results:

Physical functioning, pain, and role functioning were the most impactful attributes on utility across all countries.
Nausea, fatigue, and bowel problems had the largest impact among cancer-specific dimensions.
Utility values for the worst health state varied significantly: -0.111 (Austria), 0.025 (Italy), and 0.048 (Poland). Austrian utilities were consistently lower for impaired health states.

Conclusions:

Cancer-specific utility values (QLU-C10D) can now be derived in Austria, Italy, and Poland.
Significant country-specific differences in utility values necessitate careful consideration when applying non-country-specific value sets in economic evaluations.