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Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

142
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
142
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

172
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
172
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

192
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
192
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

159
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
159
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

284
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
284
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

256
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
256

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Related Experiment Video

Updated: Dec 20, 2025

In vivo Near Infrared Fluorescence NIRF Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis
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Imaging and Targeting Coronary Artery Inflammation.

Henry W West1, Charalambos Antoniades1

  • 1Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.

Antioxidants & Redox Signaling
|May 28, 2020
PubMed
Summary

Coronary artery disease (CAD) is a major health concern. New research explores inflammation

Keywords:
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Area of Science:

  • Cardiovascular Medicine
  • Immunology
  • Medical Imaging

Background:

  • Coronary artery disease (CAD) remains a leading cause of death globally.
  • Residual risk in CAD is increasingly linked to inflammatory mechanisms.
  • Current therapies do not fully address inflammation-driven atherosclerosis.

Purpose of the Study:

  • To review the latest evidence on inflammation in coronary artery atherosclerosis.
  • To update on noninvasive methods for assessing coronary artery inflammation.
  • To examine targeted therapies for treating coronary inflammation and reducing CAD risk.

Main Methods:

  • Review of current scientific literature on inflammation, imaging, and therapeutics in CAD.
  • Analysis of advances in computed tomography (CT), positron emission tomography (PET), and ultrasound for detecting coronary inflammation.
  • Evaluation of novel anti-inflammatory and pro-resolution therapies for atherosclerosis.

Main Results:

  • Inflammatory processes significantly contribute to the development and progression of coronary artery atherosclerosis.
  • Noninvasive imaging techniques show promise for identifying and monitoring coronary inflammation.
  • Targeted anti-inflammatory therapies are under investigation for their efficacy and safety in managing CAD.

Conclusions:

  • Understanding inflammation is crucial for managing residual CAD risk.
  • Advances in noninvasive imaging will improve patient selection and treatment monitoring.
  • Developing effective anti-inflammatory treatments is a key future direction for reducing CAD burden.