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Successful therapeutic approach in a patient with elephantiasic pretibial myxedema

Marina Ferreira1, Luciana Helena Zacaron1, Annair Freitas do Valle1

  • 1University Hospital, Universidade Federal de Juiz de Fora, Juiz de Fora, MG, Brazil.

Anais Brasileiros De Dermatologia
|May 29, 2020
PubMed

Localized pretibial myxedema is a dermopathy whose treatment is a challenge in dermatology, occurring in 0.5-4% of patients with Graves' disease. This autoimmune thyroid condition stimulates the production of hyaluronic acid and glycosaminoglycans that are deposited particularly in the pretibial region. Clinically, it presents as a localized, circumscribed, and non-depressible infiltrate in plaques. Several treatment modalities have been proposed, and their results vary, with worse response observed in severe cases. This report presents the case of a patient with elephantiasic pretibial myxedema who was subjected to intralesional corticosteroid applications, resulting in an excellent and encouraging therapeutic response that was maintained.

Keywords:
Evaluation of results of therapeutic interventionsMyxedemaSteroidsTherapeutics

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