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Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
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Left Ventricular Thrombus in Myocardial Infarction After Successful Primary Percutaneous Coronary Intervention:

Sheeren Khaled1,2, Zeineb Hachicha1, Osama Elkhateeb3

  • 1Cardiac Center, King Abdullah Medical City, Makkah, Saudi Arabia.

CJC Open
|May 29, 2020
PubMed

Insights

Left ventricular thrombus (LVT) frequently complicates ST-elevation myocardial infarction. Key predictors include left anterior descending infarct and severe systolic dysfunction, independent of revascularization strategy.

Area of Science:

  • Cardiology
  • Cardiovascular Research
  • Medical Imaging

Background:

  • Left ventricular thrombus (LVT) is a known complication of myocardial infarction.
  • Screening for LVT is important due to its impact on patient outcomes.

Purpose of the Study:

  • To identify predictors of early left ventricular thrombus formation after acute ST-elevation myocardial infarction.
  • To evaluate the role of revascularization strategies in LVT development.

Main Methods:

  • Retrospective study of 308 patients with acute ST-elevation myocardial infarction treated with primary percutaneous coronary intervention.
  • Early screening for LVT using echocardiography and cardiac magnetic resonance.

Main Results:

  • 11.7% of patients developed LVT.
  • Independent predictors of LVT were left anterior descending-related infarct (OR 10.17) and severe left ventricular systolic dysfunction (OR 8.3).
  • Lower left ventricular ejection fraction correlated with higher LVT risk; multivessel disease and revascularization strategy were not predictive.

Conclusions:

  • Early LVT is common post-ST-elevation myocardial infarction despite intervention.
  • Left anterior descending infarct and severe LV systolic dysfunction are key predictors.
  • Further research is needed on environmental factors and LVT risk.
Abstract

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