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Updated: Dec 20, 2025

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Published on: August 17, 2016
Patterns of enhancement in the hepatobiliary phase of gadoxetic acid-enhanced MRI
Cathryn L Hui1, Marcela Mautone
1Diagnostic Imaging Department, Monash Health, Melbourne, Australia.
Abstract:
A variety of patterns of enhancement of liver lesions and liver parenchyma is observed in the hepatobiliary phase (HBP) of gadoxetic acid-enhanced MRI. It is becoming increasingly apparent that many lesions may exhibit HBP enhancement. Much of the literature regarding the role of gadoxetic acid-enhanced MRI in characterising liver lesions is dichotomous, focusing on whether lesions are enhancing or non-enhancing in the HBP, rather than examining the patterns of enhancement. We provide a pattern-based description of HBP enhancement of liver parenchyma and of liver lesions. The role of OATP1B3 transporters, hepatocyte function and lesion composition in influencing patterns of HBP hyperintensity are discussed.
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