Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Symbiosis

Symbiosis

Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hierarchical Cd4SiS6/SiO2 Heterostructure Nanowire Arrays.

Nanoscale research letters·2010

Same author

Differential roles of PKA and Epac on the production of cytokines in the endotoxin-stimulated primary cultured microglia.

Journal of molecular neuroscience : MN·2010

Same author

Discovery of potent, selective, and orally bioavailable 3H-spiro[isobenzofuran-1,4'-piperidine] based melanocortin subtype-4 receptor agonists.

Bioorganic & medicinal chemistry letters·2010

Same author

Evolution of the catalytic activity of Arabidopsis thaliana glutathione transferase zeta class-1 by saturation mutagenesis.

Bioscience, biotechnology, and biochemistry·2010

Same author

Preactivation-based, one-pot combinatorial synthesis of heparin-like hexasaccharides for the analysis of heparin-protein interactions.

Chemistry (Weinheim an der Bergstrasse, Germany)·2010

Same author

Optimization of privileged structures for selective and potent melanocortin subtype-4 receptor ligands.

Bioorganic & medicinal chemistry letters·2010

Search research articles

Related Experiment Video

Updated: Dec 20, 2025

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei

Published on: February 17, 2014

Backward bifurcation in a malaria transmission model.

Yanyuan Xing^1,2, Zhiming Guo¹, Jian Liu¹

¹School of Mathematics and Information Science, Guangzhou University, Guangzhou, People's Republic of China.

Journal of Biological Dynamics

|May 29, 2020

Summary

This study introduces a malaria transmission model highlighting limited resource impacts. The research explores disease dynamics, stability, and potential backward bifurcation in human and mosquito populations.

Keywords:

92D30 Global stability backward bifurcation basic reproductive number limited resource malaria transmission

More Related Videos

Protocol for Production of a Genetic Cross of the Rodent Malaria Parasites

Protocol for Production of a Genetic Cross of the Rodent Malaria Parasites

Published on: January 3, 2011

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Published on: July 4, 2007

Related Experiment Videos

Last Updated: Dec 20, 2025

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei

Published on: February 17, 2014

Protocol for Production of a Genetic Cross of the Rodent Malaria Parasites

Protocol for Production of a Genetic Cross of the Rodent Malaria Parasites

Published on: January 3, 2011

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Published on: July 4, 2007

Area of Science:

Epidemiology
Mathematical Biology
Disease Modeling

Background:

Malaria remains a significant global health challenge, necessitating robust transmission models.
Understanding the influence of resource limitations on disease dynamics is crucial for effective control strategies.

Purpose of the Study:

To develop and analyze a mathematical model for malaria transmission dynamics.
To investigate the impact of limited resources on disease spread in human and mosquito populations.
To determine conditions for disease eradication and persistence.

Main Methods:

Formulation of a compartmental mathematical model for malaria transmission.
Derivation of the basic reproductive number (R0).
Analysis of model equilibria and stability using bifurcation theory.
Numerical simulations to validate analytical findings.

Main Results:

The model characterizes malaria transmission dynamics considering resource limitations.
Conditions for the existence of a disease-free equilibrium and endemic equilibria were established.
The model demonstrates the possibility of backward bifurcation, where a stable disease-free state coexists with an endemic state.
Conditions for global asymptotic stability of both disease-free and endemic equilibria were determined.

Conclusions:

Limited resources can significantly influence malaria transmission patterns.
The potential for backward bifurcation highlights complex disease dynamics and challenges in eradication.
The model provides valuable insights for public health interventions and resource allocation in malaria control programs.