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Multisystem Inflammatory Syndrome in Children During the Coronavirus 2019 Pandemic: A Case Series

Kathleen Chiotos1,2,3, Hamid Bassiri2,3, Edward M Behrens4

  • 1Division of Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Journal of the Pediatric Infectious Diseases Society
|May 29, 2020
PubMed

Insights

Multisystem inflammatory syndrome in children (MIS-C) can cause fever, diarrhea, and shock in critically ill youth. Other symptoms may include rash, red eyes, swelling, and mouth sores.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Multisystem inflammatory syndrome in children (MIS-C) is a rare but serious condition.
  • It is characterized by widespread inflammation affecting multiple organ systems.

Observation:

  • This case series describes 6 critically ill pediatric patients diagnosed with MIS-C.
  • The patients presented with a constellation of severe symptoms.

Findings:

  • Key clinical manifestations included fever, diarrhea, and shock.
  • Variable symptoms observed were rash, conjunctivitis, extremity edema, and mucous membrane changes.

Implications:

  • Early recognition and prompt management are crucial for improving outcomes in children with MIS-C.
  • Understanding the diverse clinical spectrum aids in timely diagnosis and treatment strategies.

Keywords:
COVID-19Kawasaki diseaseSARS-CoV-2multisystem inflammatory syndrome in children

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