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Updated: Dec 20, 2025

A Novel Method: Super-selective Adrenal Venous Sampling

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Published on: September 15, 2017

Adrenal paracoccidioidomycosis

Alejandro Román-González¹, Juan Pablo Toro², Luis F Arias³

¹Departamento de Medicina Interna, Hospital Universitario San Vicente Fundación, Universidad de Antioquia, Medellín, Colombia. alejoroman@gmail.com.

Biomedica : Revista Del Instituto Nacional De Salud

|May 29, 2020

Summary

Primary adrenal insufficiency, characterized by low cortisol and aldosterone, can stem from infections. This case highlights paracoccidioidomycosis as a rare cause of adrenal insufficiency, confirmed via imaging and biopsy.

Keywords:

Paracoccidioidomycosis adrenal glands hydrocortisone prednisone prednisolone

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Area of Science:

Endocrinology
Infectious Diseases
Medical Imaging

Background:

Primary adrenal insufficiency involves deficient production of glucocorticoids, mineralocorticoids, and sexual androgens, leading to hormonal imbalances.
Common causes include autoimmune conditions targeting 21-hydroxylase and infectious agents, particularly in resource-limited regions.

Observation:

This article details a case of adrenal insufficiency diagnosed through computerized tomography (CT) and adrenal biopsy.
The patient presented with characteristic symptoms of adrenal insufficiency.

Findings:

The diagnostic workup, including CT scans and adrenal biopsy, identified paracoccidioidomycosis as the underlying cause of the patient's adrenal insufficiency.
Paracoccidioidomycosis is a fungal infection that can affect the adrenal glands.

Implications:

This case underscores the importance of considering infectious etiologies, including rare fungal infections like paracoccidioidomycosis, in the differential diagnosis of adrenal insufficiency.
Accurate diagnosis through advanced imaging and histopathology is crucial for effective management of adrenal insufficiency.
Expanding the understanding of infectious causes of adrenal insufficiency can improve patient outcomes globally.