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Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins

Published on: August 31, 2019

A systematic study on chitosan-liposome based systems for biomedical applications.

Santosh Kumar¹, Joydeep Dutta², P K Dutta³

¹Division of Chemical Engineering, Konkuk University, Seoul 05029, South Korea.

International Journal of Biological Macromolecules

|May 29, 2020

Summary

Researchers are exploring chitosan-liposome systems to overcome the poor stability and drug leakage issues associated with traditional liposomes for enhanced drug delivery applications.

Keywords:

Biomedical applications Chitosan Liposomes

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Area of Science:

Biomaterials Science
Drug Delivery Systems
Nanotechnology

Background:

Liposomes are promising drug delivery vehicles but suffer from poor stability and drug leakage.
Surface modification of liposomes is crucial for improving their performance in biomedical applications.

Purpose of the Study:

To review the preparation methods for chitosan-liposome based systems.
To discuss the potential biomedical applications of these novel systems.

Main Methods:

Literature review focusing on chitosan-liposome system preparation.
Analysis of existing studies on chitosan-liposome formulations and applications.

Main Results:

Chitosan modification enhances liposome stability and controls drug release.
Chitosan-liposome systems show potential in various biomedical fields.

Conclusions:

Chitosan-liposome systems offer a viable strategy to address liposome limitations.
Further research into chitosan-liposome systems is warranted for advanced drug delivery.