Related Experiment Video
Updated: Dec 20, 2025
Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
Published on: August 11, 2017
Multitechnology Biofabrication: A New Approach for the Manufacturing of Functional Tissue Structures?
Miguel Castilho1, Mylène de Ruijter2, Stephen Beirne3
1Department of Orthopaedics, University Medical Center Utrecht, Utrecht, The Netherlands; Orthopaedic Biomechanics, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands; Regenerative Medicine Center Utrecht, Utrecht, The Netherlands.
Abstract:
Most available 3D biofabrication technologies rely on single-component deposition methods, such as inkjet, extrusion, or light-assisted printing. It is unlikely that any of these technologies used individually would be able to replicate the complexity and functionality of living tissues. Recently, new biofabrication approaches have emerged that integrate multiple manufacturing technologies into a single biofabrication platform. This has led to fabricated structures with improved functionality. In this review, we provide a comprehensive overview of recent advances in the integration of different manufacturing technologies with the aim to fabricate more functional tissue structures. We provide our vision on the future of additive manufacturing (AM) technology, digital design, and the use of artificial intelligence (AI) in the field of biofabrication.
