Related Experiment Video
Updated: Dec 20, 2025

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Squamous Cell Carcinoma Arising from Sinonasal Inverted Papilloma.
D T Ginat1, A Trzcinska2, P Horowitz3
1From the Departments of Radiology, Section of Neuroradiology (D.T.G.) dtg1@uchicago.edu.
Malignant transformation of sinonasal inverted papillomas into squamous cell carcinoma can be detected using CT and MRI. Imaging features like bone erosion and necrosis suggest malignancy, aiding diagnosis when biopsies are insufficient.
Area of Science:
- Otolaryngology
- Radiology
- Pathology
Background:
- Sinonasal inverted papillomas (SNIPs) can rarely become malignant.
- Malignant transformation is often to squamous cell carcinoma (SCC).
- EGFR mutations are sometimes associated with this transformation.
More Related Videos
07:29Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
10:26RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Nose and Nasal Cavity
Cranial Bones: Lateral View
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Olfactory Receptors: Location and Structure
Anatomy of Respiratory System I: Upper Respiratory Tract
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....